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  • substructure searching in tables where sortedchemindex is applied gives back the hits quickly in relevance-sorted order, that is hits that are most similar to the query molecule are returned first
  • similarity searching in tables where sortedchemindex is applied is also much quicker, especially when narrow similarity threshold is defined
  • indexing time is longer (approximately 1.7 times) in case of sortedchemindex
  • returning all hits in searches can be faster if chemindex was applied

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