The dimension of a molecule can be interpreted topologically, based on the connections of the consisting atoms, or spatially, based on their Cartesian coordinates.
Molecules with same connectivity but different spatial arrangement are called stereoisomers.
Enantiomers: Molecules that are non-superimposable, complete mirror images of each other.
Diastereomers: Stereoisomers that are not enantiomers.
Non-carbon tetrahedral stereocenters
Ammonium and phosphonium salts
Amine oxides and phosphanones
In this case the lone pair of phosphorus atom is considered as the fourth ligand.
Phosphates and phosphonates
An atom in a ring is a tetrahedral center, if
the central atom has 2 different kinds of ligands outside the ring, and
the graph invariant of the ring is not the same in the two sides of the central atom, or
the graph invariant of the ring is the same in the two sides of the central atom, but
the ring contains even numbers of atoms (including the parity central atom), or
there is an atom with nonzero parity in the opposite side of the ring:
Nitrogen atoms in a ring is tetrahedral stereo center, if
N is a tetrahedral stereo center in a 3 membered ring,
0D: Stereoinformation is defined in 0 dimension by parity.
2D: Stereoinformation in 2 dimension is defined by wedge, hatch or wiggly bond types.
An atom in the molecule around which the ligands are arranged so that interchange of two ligands leads to stereoisomer is called stereocenter or stereogenic center . Chirality appears in stereoisomerism which is due to tetrahedral stereogenic centers. These centers can have point chirality. The ligands of the chiral center are assigned a priority based on the Cahn-Ingold-Prelog priority rules. Each chiral center is then labeled by R or S based on the orientation of the assigned numbers. The center is oriented so that the lowest-priority is pointed away from the viewer. If the priority of the remaining three substituents decreases clockwise, it is labeled R , otherwise, if it decreases counter clockwise, it is S .
Pseudo-asymmetric atoms which are invariant on reflection in a mirror are labeled by r/s descriptors:
Nomenclature of Organic Chemistry: IUPAC Recommendations and Preferred Names 2013 (Eds:Henri A. Favre, Warren H. Powell) Chapter P-9 Specification of Configuration and Conformation Royal Society of Chemistry
Wikipedia: Cahn-Ingold-Prelog priority rules.